🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧪 Experimental Design

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Trial Search

Current Search Criteria:

Intervention: EC-MPS, Tacrolimus

Found 15 matching trials

A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients

PHASE4

This study will assess whether a calcineurin inhibitor (CNI)-free regimen w...

Status

Completed

Location

Novartis Investigative Site

Start Date

2009-02-24

Trial ID

NCT00862979

Treatments Being Tested

Everolimus (EVR)cyclosporine A (CyA)tacrolimus (TAC)Enteric coated mycophenolate sodium (EC-MPS)mycophenolate mofetil (MMF)Corticosteroids

Enteric-coated Mycophenolate Sodium (EC-MPS) With Reduced-dose Tacrolimus Versus EC-MPS With Standard-dose Tacrolimus in Stable Kidney Transplant Recipients

PHASE3

This study introduces a new optimization immunosuppressive regimen associat...

Status

Completed

Location

Novartis

Start Date

2005-12

Trial ID

NCT00284934

Treatments Being Tested

Enteric-coated mycophenolate sodium (EC-MPS)Tacrolimus Corticosteroids

Tacrolimus and Personalized Therapy to Prevent Acute Rejection Episodes

N/A

Heart transplant is the only effective treatment for people with advanced h...

Status

Unknown

Location

Fondazione IRCCS Policlinico San Matteo

Start Date

2022-01-07

Trial ID

NCT06338306

Treatments Being Tested

Tacrolimus（FK506）

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients

PHASE2

This study was to compare CFZ533 to tacrolimus (TAC) in prevention of organ...

Status

Completed

Location

Novartis Investigative Site

Start Date

2018-11-28

Trial ID

NCT03663335

Treatments Being Tested

CFZ533 - Cohort 1/Cohort 2 Mycophenolate Mofetil (MMF)Corticosteroids (CS)Tacrolimus Induction therapy: basiliximab Induction therapy: rabbit anti-thymocyte globulin (rATG)Maintenance population: EC-MPS Maintenance population: MMF Placebo 1 mL

Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies

PHASE3

Induction therapy decreases the rate of acute allograft rejection in kidney...

Status

Recruiting

Location

01-TOURS

Start Date

2023-11-07

Trial ID

NCT05385432

Treatments Being Tested

Rabbit Anti thymocyte globulin (rATG)Basiliximab

Comparison of CNI-based Regimen Versus CNI-free Regimen in Kidney Transplant Recipients.

PHASE4

Calcineurin inhibitors (CNI), a potent immunosuppressive drug used in kidne...

Status

Terminated

Location

Novartis Investigative Site

Start Date

2005-11

Trial ID

NCT00332839

Treatments Being Tested

Everolimus Cyclosporin A (CsA)Tacrolimus Enteric Coated - Mycophenolate Sodium (EC-MPS)Corticosteroids

Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate Sodium

PHASE3

A recent therapeutic strategy following renal transplantation includes simu...

Status

Completed

Location

University of Miami

Start Date

2012-11

Trial ID

NCT01680861

Treatments Being Tested

Tacrolimus Everolimus Enteric Coated Mycophenolate Sodium (EC-MPS)Corticosteroids

A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients

PHASE3

The aims of the study was to evaluate the safety and efficacy of early intr...

Status

Completed

Location

Novartis Investigative Site

Start Date

2012-12

Trial ID

NCT01625377

Treatments Being Tested

tacrolimus everolimus Basiliximab Mycophenolic Acid Corticosteroids

Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in Kidney Transplant Recipients

PHASE4

This study will investigate the safety, tolerability and efficacy of EC-MPS...

Status

Completed

Location

Novartis

Start Date

2005-09

Trial ID

NCT00229138

Treatments Being Tested

EC-MPS, Tacrolimus

A Study to Investigate the Tolerability and Safety of Converting Stable Renal Transplant Recipients Who Receive Tacrolimus With or Without Corticosteroids From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS)

PHASE4

The aim of this study is whether a switch of stable renal transplant recipi...

Status

Completed

Location

Multiple Locations

Start Date

2003-01

Trial ID

NCT00238979

Treatments Being Tested

Enteric-Coated Mycophenolate Sodium (EC-MPS)

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